Aureus databases coverage
Articles and patents are selected based on keywords in the title or in the abstract from a set of four key structure-activity journals.
In addition, the tables of content of principal pharmacological journals are also screened to select important articles in which SAR data has been published.
On the other hand, regular PubMed queries on “hot” or new targets or on missing compounds are made to collect additional references of interest.
These articles are carefully analyzed and data is recorded by Aureus’ scientific analysts.
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ADME database
A unique knowledgebase containing ADME properties and drug-drug interactions.Kinases database
The Kinases modulators have significant potential in treating diseases including cancer, inflammatory disorders or diabetes.Nuclear Receptors database
Nuclear receptors form a family of ligand-activated transcription factors that regulate a wide variety of biological processes.Proteases database
Human pathologies resulting from protease disorders include such diseases as cancer, dementia, stroke, periodontitis and arthritis.
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GPS database
The Global Pharmacology Database is an extensive knowledge base containing quantitative biological activity data for major therapeutic drug targets.Ion Channels database
ICHN modulators are currently used for the treatment of several diseases. Physiologically, ion channels are key components in processes involving rapid cell changes.GPCR database
GPCR account for approximately one-third of all approved drugs. Challenges in drug discovery include de-orphanization of candidate drug targets, and exploring the field of allosteric modulation.
